Prevalence and risk factors for avian influenza virus (H5 and H9) contamination in peri-urban and rural live bird markets in BangladeshArticle Published on 2023-04-202023-06-02 Journal: Frontiers in Public Health [Category] 조류인플루엔자, [키워드] Avian influenza virus Bangladesh Biosecurity practices environmental contamination landscape Live bird markets Risk factors zoonoses. [DOI] 10.3389/fpubh.2023.1148994 PMC 바로가기
The Peripheral Immune Landscape in a Patient with Myocarditis after the Administration of BNT162b2 mRNA VaccineArticle Published on 2022-10-312022-11-15 Journal: Molecules and cells [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] acute respiratory syndrome analysis approved BNT162b2 BNT162b2 mRNA vaccination causes cell clusters change changes in complications coronavirus Differentially expressed genes global public health help IL7R immune increased expression increased risk landscape Messenger RNA monocyte mononuclear cell mRNA myocarditis of BNT162b2 pandemic Pathogenesis Patient PBMC PBMCs peripheral Peripheral blood peripheral blood mononucleear cells reported Research SARS-CoV-2 Sequencing severe acute respiratory syndrome coronavirus 2 single-cell Single-cell RNA sequencing single-cell RNA sequencing. T cell receptor Transcriptome transcriptomic profile vaccinated individual vaccination Vaccine [DOI] 10.14348/molcells.2022.0031 PMC 바로가기
Multiplex Detection of Antibody Landscapes to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)/Influenza/Common Human Coronaviruses Following Vaccination or Infection With SARS-CoV-2 and InfluenzaArticle Published on 2022-10-032022-11-15 Journal: Clinical Infectious Diseases: An Official Publicat [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] acute respiratory illness acute respiratory syndrome Adsorption analyzed antibody antibody immunity antibody landscape Antibody Response ARI Clinical presentations collected common human coronaviruses coronavirus coronavirus 2 cross-reactive antibody detection exhibited Human human coronavirus human coronaviruses in-depth analysis individual Infection Influenza influenza infection influenza vaccine influenza virus landscape Last multiplex multiplex detection. no interaction protective immunity public health threat representing respiratory respiratory infection response responses SARS-CoV-2 SARS-CoV-2 infections SARS-CoV-2 vaccination Sensitivity and specificity sera serological evidence serum Spike protein vaccination Vaccine [DOI] 10.1093/cid/ciac472 PMC 바로가기
Characterizing the Spatiotemporal Heterogeneity of the COVID-19 Vaccination LandscapeArticle Published on 2022-09-282022-11-16 Journal: American journal of epidemiology [Category] SARS, 변종, [키워드] acute respiratory syndrome center Cluster Control coronavirus coronavirus disease Coronavirus disease 2019 Coverage COVID-19 COVID-19 vaccination Critical data accuracy discrepancy effort exhibit foci growth heterogeneity IMPROVE landscape outcome prevention rising SARS-CoV-2 SARS-CoV-2 variants severe acute respiratory syndrome coronavirus 2 spatiotemporal Spatiotemporal analysis statistically the SARS-CoV-2 the United State The United States These data Transmission United States vaccination vaccination. variant widespread [DOI] 10.1093/aje/kwac080 PMC 바로가기
Pandemic-Scale Phylogenomics Reveals The SARS-CoV-2 Recombination Landscape Research Published on 2022-08-112022-10-05 Journal: Nature [Category] SARS, 변종, 치료기술, [키워드] Analysis analysis approach breakpoint detectable Epidemic events exceeded Genetic variation Genome genomic data highlight identify landscape Lineage lineages occur pandemic Phylogenetic Phylogenomics Recombination SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 phylogeny sequenced Spread the SARS-CoV-2 the spike protein Transmissibility variants of interest viral recombination virulence virus [DOI] 10.1038/s41586-022-05189-9 [Article Type] Research
Deregulation of ceRNA Networks in Frontal Cortex and Choroid Plexus of Brain during SARS-CoV-2 Infection Aggravates Neurological Manifestations: An Insight from Bulk and Single-Cell Transcriptomic AnalysesSARS-CoV-2 감염 중 뇌의 전두엽 피질 및 맥락총 신경총에서 ceRNA 네트워크의 규제 완화는 신경 증상을 악화시킵니다: 대량 및 단일 세포 전사체 분석의 통찰력Article Published on 2022-08-012022-09-11 Journal: Advanced Biology [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] analysis analyzed Brain cell type cell types choroid Choroid plexus competing competing endogenous RNA network cortex deregulated differentially expressed downregulated downregulation downstream excitatory explain Frontal Gene Expression help Human brain impairment indicated Initially insight landscape lncRNA MALAT1 mapping mechanism MIRLET7BHG miRNA miRNA. miRNAs mRNA NEAT1 network neurological Neuron neurons NorAD pathway enrichment Plexus reconstructed regulatory circuit RNA RNA-Seq SARS-CoV-2 single-cell RNA-seq STXBP5 STXBP5-AS1 therapeutic Therapeutics transcriptomic upregulated upregulation Variability [DOI] 10.1002/adbi.202101310 PMC 바로가기 [Article Type] Article
A novel method to detect the early warning signal of COVID-19 transmissionArticle Published on 2022-07-182022-11-16 Journal: BMC Infectious Diseases [Category] 치료기술, [키워드] approach Auto-reservoir neural network (ARNN) Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) COVID-19 COVID-19 disease COVID-19 infections COVID-19 transmission detect disease Diseases Early warning signals (EWS) Epidemics facilitate Health information landscape Landscape network entropy (LNE). measure network Neural number of infected outbreak Outbreaks Pandemics Patient predict Prevent Quantitative analysis spread of COVID-19 [DOI] 10.1186/s12879-022-07603-z PMC 바로가기
SARS-CoV-2 Achieves Immune Escape by Destroying Mitochondrial Quality: Comprehensive Analysis of the Cellular Landscapes of Lung and Blood Specimens From Patients With COVID-19SARS-CoV-2, 미토콘드리아 품질을 파괴하여 면역 탈출 달성: COVID-19 환자의 폐 및 혈액 표본의 세포 환경에 대한 종합 분석Article Published on 2022-07-012022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 치료제, [키워드] activated activating alveolar alveolar epithelial cell alveolar epithelial cells alveolar macrophage Alveolar macrophages analyzed antiviral immunity B cell B cells blocked Blood calcium cell count Comprehensive coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patients crossfire cytokine Cytokine storm dataset Defense Degradation energy metabolism epithelial epithelial cell epithelial cells escape exacerbated excessive inflammation explain expression Gene Expression HIF1a Host IFI27 immune immune cells Immune escape Inflammation inhibited Interaction interferon landscape lung tissue Lungs Macrophage macrophages manifestation MCU metabolic pathway metabolism Mitochondria mitochondrial mitochondrial fission mitochondrial functions mitochondrial quality. pathway patients with COVID-19 Perspective plasma pro-inflammatory Regulatory T cell regulatory T cells released Replication respiratory capacity resulting RNA-sequencing SARS-CoV-2 significant changes in Single-cell RNA-sequencing T cells target transformation Tregs type I viral infection [DOI] 10.3389/fimmu.2022.946731 PMC 바로가기 [Article Type] Article
The Translational Landscape of SARS-CoV-2-infected Cells Reveals Suppression of Innate Immune GenesSARS-CoV-2에 감염된 세포의 번역 환경은 선천 면역 유전자의 억제를 나타냅니다Article Published on 2022-06-282022-09-11 Journal: mBio [Category] COVID19(2023년), MERS, SARS, 유전자 메커니즘, 진단, [키워드] abundantly expressed acute respiratory syndrome acute respiratory syndrome coronavirus Air-liquid interface airway Cell cell cultures cell line cells cellular cellular mRNAs chemokine ciliated ciliated cell coding coronavirus cytokine downregulation event help highlight host mRNA host response host responses immune immune response immune responses infected cells Inflammatory Innate innate immune innate immune response Interaction interferon-stimulated genes involved landscape mechanism mediators modulate mRNA mRNA translation mRNAs notable primary cells programmed frameshifting regulated respiratory ribo-seq ribosomal frameshifting ribosome ribosome profiling ribosomes RNAs SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 replication SARS-CoV-2-infected cell SARS-CoV-2-infected cells sequence severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 suppression therapeutic therapeutic intervention These data transcriptional Transcriptional upregulation translated translation translation initiation translational translational repression unique upregulation Viral viral mRNA viral mRNAs virus virus replication virus-host interaction. [DOI] 10.1128/mbio.00815-22 PMC 바로가기 [Article Type] Article
Drugs and convalescent plasma therapy for COVID-19: a survey of the interventional clinical studies in Italy after 1 year of pandemicCOVID-19에 대한 약물 및 회복기 혈장 요법: 대유행 1년 후 이탈리아의 중재적 임상 연구 조사Article Published on 2022-06-222022-09-11 Journal: Trials [Category] COVID19(2023년), SARS, 신약개발, 임상, [키워드] 2019 novel coronavirus adopted AIFA Analysis carried Characteristics clinical Clinical research clinical study clinical trial clinical trials convalescent plasma Convalescent plasma therapy coronavirus disease COVID-19 COVID-19 disease Critical disease drug drugs early phase effort Evidence experimental intervention feature Follow-up Health include Intervention investigated investigator investigators Italian Italy landscape majority Medicine methodological Novel coronavirus novel coronavirus disease pandemic parallel group performed platform prevention of COVID-19 Prophylactic Randomized recommendation Registered Replication replications Research Study design therapeutic Therapeutic approach Therapeutic class. therapeutic strategy Treatment Trial trials website were blinded [DOI] 10.1186/s13063-022-06474-8 PMC 바로가기 [Article Type] Article